8 results for "Group II mGluR Agonists Small Molecules and Peptides" in 产品
Group II mGluR Agonists Small Molecules and Peptides
Metabotropic Glutamate (mGlu) group II receptors are members of the metabotropic class of glutamate receptors, which also includes mGlu group I and mGlu group III receptors. Group II receptors are divided into two subtypes, mGlu2 and mGlu3. mGlu group II receptors are coupled to Gi/o, which inhibits adenylyl cyclase, decreasing the formation of cAMP. These receptors are involved in presynaptic inhibition and do not appear to affect postsynaptic membrane potential by themselves. The human genes for mGlu2 and mGlu3 receptors have been localized to chromosomes 3 (p21.1) and 7 (7q21.1-q21.2) respectively.
Highly potent group II mGlu agonist; also NMDA agonist
| Chemical Name: | (2S,2'R,3'R)-2-(2',3'-Dicarboxycyclopropyl)glycine |
| Purity: | ≥98% |
Competitive group I mGlu antagonist; also weak group II agonist
| Alternate Names: | (S)-4CPG |
| Purity: | ≥98% |
Potent and highly selective group II mGlu agonist
| Chemical Name: | (1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid |
| Purity: | ≥98% |
Highly selective group II agonist
| Chemical Name: | (2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylate |
| Purity: | ≥98% |
Potent group II mGlu agonist
| Alternate Names: | (2S,3S,4S)-CCG |
| Chemical Name: | (2S,1'S,2'S)-2-(Carboxycyclopropyl)glycine |
| Purity: | ≥99% |
Highly selective group II mGlu agonist
| Chemical Name: | (1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid |
| Purity: | ≥99% |
Selective group II mGlu agonist; sodium salt of LY 379268 (Cat. No. 2453)
| Chemical Name: | (1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid disodium salt |
| Purity: | ≥98% |
Group I and II mGlu agonist
| Chemical Name: | (±)-1-Aminocyclopentane-trans-1,3-dicarboxylic acid |
| Purity: | ≥99% |
