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2 results for "ITK Inhibitors Small Molecules and Peptides" in 产品
ITK Inhibitors Small Molecules and Peptides
ITK (IL-2-inducible T-cell kinase) EC 2.7.10.2 is a member of the Tec family of nonreceptor tyrosine kinases, which includes Bruton's tyrosine kinase. It is critical for the growth, differentiation and activation of T-cells. ITK is expressed in T-lymphocytes and acts downstream from T-cell receptor (TCR) stimulation. Activation of PI 3-kinase results in the accumulation of PIP3, which in turn leads to the recruitment of ITK to the membrane, its activation and subsequent ...
Potent ITK inhibitor; also inhibits BTK
| Chemical Name: | (R)-3-(1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-N-(3-methyl-4-(1-methylethyl))benzamide |
| Purity: | ≥95% |
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ITK inhibitor
| Chemical Name: | 1,5-Dihydro-7-(phenylmethyl)-1-[3-(1-piperidinyl)propyl]-2-[4-(4-pyridinyl)phenyl]-6H-imidazo[4,5-g]quinoxalin-6-one |
| Purity: | ≥98% |
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