13 results for "Kainate Receptor Antagonists Small Molecules and Peptides" in 产品
Kainate Receptor Antagonists Small Molecules and Peptides
Kainate receptors are cation-selective, ligand-gated ion channels, which cause a strong membrane depolarization in response to glutamate binding. Like other members of the ionotropic glutamate receptor family, they are named for their specific activation by kainate (kainic acid), which was initially isolated from the algae Digenea simplex.
Kainate receptors exist as tetramers, composed of the subunits GluK1 to 5. Each subunit has an extracellular N-terminus, a cytoplasmic C-terminus, three ...
Potent and selective non-NMDA iGluR antagonist
| Alternate Names: | Cyanquixaline |
| Chemical Name: | 6-Cyano-7-nitroquinoxaline-2,3-dione |
| Purity: | ≥98% |
Potent non-NMDA iGluR antagonist; more water soluble form of CNQX (Cat. No. 0190)
| Chemical Name: | 6-Cyano-7-nitroquinoxaline-2,3-dione disodium |
| Purity: | ≥98% |
Selective non-NMDA iGluR antagonist
| Chemical Name: | 6,7-Dinitroquinoxaline-2,3-dione |
| Purity: | ≥98% |
Selective non-NMDA iGluR antagonist; water-soluble salt of DNQX (Cat. No. 0189)
| Chemical Name: | 6,7-Dinitroquinoxaline-2,3-dione disodium salt |
| Purity: | ≥98% |
Non-competitive non-NMDA iGluR antagonist
| Chemical Name: | 1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride |
| Purity: | ≥98% |
Potent kainate antagonist; displays selectivity for GluK1-containing receptors
| Chemical Name: | (S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-5-phenylthiophene-3-yl-methyl)-5-methylpyrimidine-2,4-dione |
| Purity: | ≥98% |
Dye for assessing cell viability and blood brain barrier permeability; also EAAT inhibitor and iGluR antagonist
| Chemical Name: | 6,6-[(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)bis[4-amino- 5-hydroxy-1,3-naphthalenedisulphonic acid] tetrasodium salt |
| Purity: | ≥90% |
GluK1-selective kainate antagonist
| Chemical Name: | (S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-thiophene-3-yl-methyl)-5-methylpyrimidine-2,4-dione |
| Purity: | ≥98% |
Potent and selective kainate antagonist; selective for GluK1-containing receptors
| Chemical Name: | (RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione |
| Purity: | ≥98% |
Potent and selective kainate antagonist; active enantiomer of UBP 296 (Cat. No. 2078)
| Chemical Name: | (S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione |
| Purity: | ≥98% |
Competitive non-NMDA iGluR antagonist
| Alternate Names: | MPQX |
| Chemical Name: | [[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonic acid |
| Purity: | ≥98% |
GluK1 antagonist; inhibits carbonic anhydrase (CA) II and IV; also positive allosteric modulator of GABAA receptors
| Alternate Names: | Topamax |
| Chemical Name: | 2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate |
| Purity: | ≥98% |
Non-competitive non-NMDA iGluR antagonist
| Alternate Names: | GYKI 53773,LY 300164 |
| Chemical Name: | (8R)-7-Acetyl-5-(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine |
| Purity: | ≥98% |
