8 results for "Kir6.1 Small Molecules and Peptides" in 产品
Kir6.1 Small Molecules and Peptides
The Kir6.1 (KCNJ8) gene is essential in membrane function as it encodes an inward-rectifier potassium channel protein that is 424 amino acids long and has a mass of nearly 48 kDA. Dysfunctions in the Kir6.1 gene may be a cause of J-wave syndromes and sudden infant death syndrome (SIDS). Research is investigating its role in various diseases such as retinitis, hypoxia, pancreatitis, myocardial infarction, spasticity, leiomyoma, acute myocardial infarction, and prinzmetal angina. The Kir6.1 gene ...
Kir6 (KATP) channel blocker
| Alternate Names: | Glyburide |
| Chemical Name: | 5-Chloro-N-[2-[4-[[[(Cylcohexylamino)carbonyl]amino]sulphonyl]phenyl]ethyl]-2-methoxybenzamide |
| Purity: | ≥98% |
H1 antagonist. Also KV11.1 (hERG) and Kir6 (KATP) channel blocker
| Chemical Name: | α-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol |
| Purity: | ≥98% |
Antianginal, activates pyruvate dehydrogenase
| Alternate Names: | RS 43285 |
| Chemical Name: | N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide dihydrochloride |
| Purity: | ≥98% |
Kir6 channel (KATP) opener
| Chemical Name: | 6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide |
| Purity: | ≥98% |
Kir6 (KATP) channel opener; active enantiomer of Cromakalim
| Alternate Names: | BRL 38227 |
| Chemical Name: | (3S,4R)-3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-2H-1-benzopyran-6-carbonitrile |
| Purity: | ≥98% |
Kir6 (KATP) channel blocker
| Alternate Names: | AG-EE 623ZW |
| Chemical Name: | 2-Ethoxy-4-[2-[[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoic acid |
| Purity: | ≥98% |
Kir6 (KATP) blocker; displays high affinity for SUR1/Kir6.2 channels
| Alternate Names: | A-4166,Senaglinide |
| Chemical Name: | N-[[4-(1-Methylethyl)cyclohexyl]carbonyl]-D-phenylalanine |
Selective inhibitor of Kir6.1 KATP channels
| Chemical Name: | 1-[(4-Methyl-2-thiophen-2-yl-1,3-thiazol-5-yl)methyl]-3-thiophen-2-ylurea |
| Purity: | ≥98% |
