7 results for "mGluR7 Small Molecules and Peptides" in 产品

mGluR7 Small Molecules and Peptides

L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of ...

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Selective mGlu7 agonist

Chemical Name: N,N'-Bis(diphenylmethyl)-1,2-ethanediamine dihydrochloride
Purity: ≥99%
Selective mGlu7 agonist
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Potent group III mGlu antagonist

Chemical Name: (RS)-α-Cyclopropyl-4-phosphonophenylglycine
Purity: ≥98%
Potent group III mGlu antagonist
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Positive allosteric modulator of mGlu7 and mGlu8 receptors; also NK1 antagonist; brain penetrant

Chemical Name: 3-(2,3-Difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
Purity: ≥98%
Positive allosteric modulators of mGlu7 and mGlu8 receptors; also NK1 antagonist; brain penetrant
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Active metabolite of oxcarbazepine (Cat. No. 3864)

Alternate Names: GP 47779
Chemical Name: 10,11-Dihydro-10-hydroxy-5H-dibenz(Z)[b,f]azepin-5-carboxamide
Purity: ≥98%
Active metabolite of oxcarbazepine (Cat. No. 3864)
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Positive allosteric modulator of group I mGlu receptors

Chemical Name: (9H-Xanthen-9-ylcarbonyl)-carbamic acid butyl ester
Purity: ≥98%
Positive allosteric modulator of group I mGlu receptors
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Selective positive allosteric modulator of group III mGlu receptors

Alternate Names: ML 396
Chemical Name: N-[3-Chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide
Purity: ≥98%
Selective positive allosteric modulator of group III mGlu receptors
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Negative allosteric modulator of mGlu7 receptors; brain penetrant

Chemical Name: 6-(2,4-Dimethylphenyl)-2-ethyl-6,7-dihydro-4(5H)-benzoxazolone
Purity: ≥98%
Negative allosteric modulator of mGlu7 receptors; brain penetrant
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