4 results for "Multidrug Transporter Substrates" in 产品
Multidrug Transporter Substrates
ATP-binding cassette (ABC) transporters form one of the largest groups of paralogous protein families that have a wide diversity of functions and substrates. Specificity has been shown for small and large molecules, highly charged molecules and highly hydrophobic molecule systems such as that for polysaccharides. Multidrug transporters (MDRs) are a specific type of ABC transporter and are commonly overexpressed in cancer cells.
P-glycoprotein (P-gp, ABCB1, MDR1) is a well-characterized human ...
Activator of hM3Dq and hM4Di DREADDs
| Alternate Names: | CNO |
| Chemical Name: | 8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine |
| Purity: | ≥98% |
Activator of hM3Dq and hM4Di DREADDs; water soluble version of Clozapine N-oxide (Cat. No. 4936)
| Alternate Names: | CNO (water-soluble) |
| Chemical Name: | 8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochloride |
| Purity: | ≥99% |
Cell permeable non-fluorescent compound; green-fluorescent in living cells once hydrolyzed. Used for: cell tracing and cell viability monitoring. Application: fluorescent microscopy and flow cytometry
| Chemical Name: | N,N'-[[3',6'-Bis(acetyloxy)-oxospiro[isobenzofuran-1-(3H),9'-(9H)xanthene]-4',5'-diyl]bis(methylene)]bis[N-[2-(acetyloxy)methoxy]-2-oxoethyl]glycine 1,1'-bis[(acetyloxy)methyl] ester |
| Purity: | ≥90% |
Protein kinase C activator
| Alternate Names: | Ingenol 3-angelate,Ingenol Mebutate |
| Chemical Name: | (2Z)-2-Methyl-2-butenoic acid (1aR,2S,5R,5aS,6S,8aS,9R,10aR)-1a,2,5,5a,6,9,10,10a-octahydro-5,5a-dihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-11-oxo-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-6-yl ester |
| Purity: | ≥97% |
