58 results for "Nicotinic Acetylcholine R alpha 7/CHRNA7" in 产品

Nicotinic Acetylcholine R alpha 7/CHRNA7 Products

The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. nAChR alpha 7/CHRNA7 forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once nAChR alpha 7/CHRNA7 binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Reactivity: Human, Porcine, Bovine, Canine, Chicken, +2 More
Details: Goat IgG Polyclonal
Applications: IHC, WB, ELISA
Immunohistochemistry-Paraffin: Nicotinic Acetylcholine R alpha 7/CHRNA7 Antibody [NBP1-52375]
(2)
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Reactivity: Human, Rat
Details: Rabbit IgG Polyclonal
Applications: WB
Western Blot: Nicotinic Acetylcholine R alpha 7/CHRNA7 Antibody [NBP1-79948]
(5)
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #7F10G1
Applications: IHC, WB, ELISA, Flow
Western Blot: Nicotinic Acetylcholine R alpha 7/CHRNA7 Antibody (7F10G1)BSA Free [NBP2-61739]
(6)
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Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ELISA, ICC/IF
Nicotinic Acetylcholine R alpha 7/CHRNA7 Antibody
(3)
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Reactivity: Human, Rat
Details: Mouse IgG1 Monoclonal Clone #7F10F1
Applications: WB, ELISA, Flow
Western Blot: Nicotinic Acetylcholine R alpha 7/CHRNA7 Antibody (7F10F1)BSA Free [NBP2-61738]
(5)
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Reactivity: Human
Applications:
R&D Systems VersaClone cDNA Plasmids
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Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: WB, ICC/IF
Western Blot: Nicotinic Acetylcholine R alpha 7/CHRNA7 Antibody [NBP1-80092]
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Reactivity: Human
Source: Wheat germ
Applications: WB, ELISA, AP, MA, PAGE
SDS-PAGE: Recombinant Human Nicotinic Acetylcholine R alpha 7/CHRNA7 Protein [H00001139-Q01]
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Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC
Immunohistochemistry-Paraffin: Nicotinic Acetylcholine R alpha 7/CHRNA7 Antibody [NBP2-99069]
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Reactivity: Human
Sensitivity: 0.112 ng/mL (example only; lot dependent)
Assay Range: 0.312 - 20 ng/mL (example only; lot dependent)
Applications: ELISA
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Reactivity: Human
Sensitivity: 0.112 ng/mL (example only; lot dependent)
Assay Range: 0.312 - 20 ng/mL (example only; lot dependent)
Applications: ELISA
Human Nicotinic Acetylcholine R alpha 7/CHRNA7 - Ready-To-Use ELISA Kit (Colorimetric)
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Selective α7 neuronal nAChR antagonist

Alternate Names: MLA
Chemical Name: [1α,4(S),6β,14α,16β]-20-Ethyl-1,6,14,16-tetramethoxy-4-[[[2-(3-methyl-2,5-dioxo-1-pyrrolidinyl)benzoyl]oxy]methyl]aconitane-7,8-diol citrate
Purity: ≥95%
Selective α7 neuronal nAChR antagonist
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Broad spectrum glutamatergic antagonist

Chemical Name: 4-Hydroxyquinoline-2-carboxylic acid
Purity: ≥98%
Broad spectrum glutamatergic antagonist
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Selective α7 nAChR antagonist

Alternate Names: α-Bgtx,α-BuTX
Purity: ≥98%
Selective α7 nAChR antagonist
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Positive allosteric modulator of α7 nAChRs; active in vivo

Chemical Name: N-(5-Chloro-2-hydroxyphenyl)-N'-[2-chloro-5-(trifluoromethyl)phenyl]urea
Purity: ≥98%
Positive allosteric modulator of α7 nAChRs; active in vivo
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Selective α7 nAChR agonist

Chemical Name: N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide
Purity: ≥98%
Selective α7 nAChR agonist
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Positive allosteric modulator of α7 nAChRs; active in vivo

Chemical Name: N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea
Purity: ≥98%
Positive allosteric modulator of α7 nAChRs; active in vivo
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Potent and selective α7 nAChR agonist

Chemical Name: N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-furo[2,3-c]pyridine-5-carboxamide hydrochloride
Purity: ≥98%
Potent and selective α7 nAChR agonist
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Selective α7 nAChR agonist

Chemical Name: N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-2,3-dihydro-1,4-benzodioxin-6-carboxamide fumarate
Purity: ≥98%
Selective α7 nAChR agonist
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Potent 5-HT3 antagonist; also α7 nAChR partial agonist

Alternate Names: Novaban,ICS 205930
Chemical Name: (3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylic acid ester monohydrochloride
Purity: ≥98%
Potent 5-HT3 antagonist; also α7 nAChR partial agonist
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α7 nAChR partial agonist

Chemical Name: 2-[2-(4-Bromophenyl)-2-oxoethyl]-1-methylpyridinium iodide
Purity: ≥98%
α7 nAChR partial agonist
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Potent α4β4, α4β2 and α7 nAChR agonist

Chemical Name: (1R,5S)-9-Bromo-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one
Purity: ≥98%
Potent α4β4, α4β2 and α7 nAChR agonist
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Positive allosteric modulator of α7 nAChRs

Alternate Names: XY 4083
Chemical Name: [N-(4-Chlorophenyl)]-α-[(4-chlorophenyl)-aminomethylene]-3-methyl-5-isoxazoleacetamide
Positive allosteric modulator of α7 nAChRs
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Allosteric potentiator of α7, α4β2 and α4β4 nAChRs

Chemical Name: [2-[(4-Fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienylmethanone
Purity: ≥98%
Allosteric potentiator of α7, α4β2 and α4β4 nAChRs
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α7 nAChR partial agonist

Chemical Name: Octahydro-2-methyl-5-(6-phenyl-3-pyridazinyl)-pyrrolo[3,4-c]pyrrole
Purity: ≥98%
α7 nAChR partial agonist
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