244 results for "P2X7/P2RX7" in 产品
P2X7/P2RX7 Products
P2RX7 belongs to the family of purinoceptors for ATP. It functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. P2RX7 antagonists have emerged as novel therapeutics for the treatment of acute inflammation, pain and fever, with wider anti-inflammatory activity than currently used cyclooxygenase inhibitors.
Photoaffinity label for ATPase; also P2X7 agonist and P2X1/P2Y1 partial agonist
| Chemical Name: | 2'(3')-O-(4-Benzoylbenzoyl)adenosine-5'-triphosphate tri(triethylammonium) salt |
| Purity: | ≥95% |
Competitive P2X7 antagonist
| Chemical Name: | 3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine hydrochloride |
| Purity: | ≥98% |
Potent and selective P2X7 antagonist
| Chemical Name: | N-[1-[[(Cyanoamino)(5-quinolinylamino)methylene]amino]-2,2-dimethylpropyl]-3,4-dimethoxybenzeneacetamide |
| Purity: | ≥97% |
| Reactivity: | Human, Mouse, Rat, Monkey |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
Non-competitive P2X7 antagonist
| Chemical Name: | 4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl] phenyl isoquinolinesulfonic acid ester |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #7G1D6 |
| Applications: | IHC, WB, ELISA, Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
Potent and selective human P2X7 antagonist
| Chemical Name: | 3-[1-[[(3'-Nitro[1,1'-biphenyl]-4-yl)oxy]methyl]-3-(4-pyridinyl)propyl]-2,4-thiazolidinedione |
| Purity: | ≥98% |
Potent P2X7 antagonist
| Chemical Name: | N-[2-[[2-[(2-Hydroxyethyl)amino]ethyl]amino]-5-quinolinyl]-2-tricyclo[3.3.1.13,7]dec-1-ylacetamide dihydrochloride |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #CL11508 |
| Applications: | IHC, WB |
Potent and selective P2X7 antagonist
| Chemical Name: | N-Cyano-N"-[(1S)-1-phenylethyl]-N'-5-quinolinyl-guanidine |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #545205 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #1058610 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #CL11508 |
| Applications: | IHC, WB |
Cell-permeable protein kinase C inhibitor
| Chemical Name: | 1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium chloride |
| Purity: | ≥98% |
Potent and selective P2X7 antagonist; brain penetrant
| Chemical Name: | 2-(Phenylthio)-N-[[tetrahydro-4-(4-phenyl-1-piperazinyl)-2H-pyran-4-yl]methyl-3-pyridinecarboxamide |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #545230 |
| Applications: | ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #1058613 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human |
| Reactivity: | Rat |
| Reactivity: | Human |
| Source: | Wheat germ |
| Applications: | WB, ELISA, AP, DB, MA |