17 results for "TRPV Antagonists" in 产品

TRPV Antagonists

TRPV antagonist; also activator of ENaCδ

Chemical Name: N-[2-(4-Chlorophenyl)ethyl]-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide
Purity: ≥98%
TRPV antagonist; also activator of ENaCδ
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Potent and selective TRPV1 competitive antagonist

Chemical Name: (2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propenamide
Purity: ≥98%
Potent and selective TRPV1 competitive antagonist
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Potent and selective TRPV1 competitive antagonist

Chemical Name: 4'-Chloro-3-methoxycinnamanilide
Purity: ≥98%
Potent and selective TRPV1 competitive antagonist
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Potent and selective TRPV4 antagonist

Chemical Name: 2-Methyl-1-[3-(4-morpholinyl)propyl]-5-phenyl-N-[3-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide
Purity: ≥98%
Potent and selective TRPV4 antagonist
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Potent and selective TRPV4 antagonist; orally active

Chemical Name: 3-([1,4'-Bipiperidin]-1'-ylmethyl)-7-bromo-N-(1-phenylcyclopropyl)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxamide
Purity: ≥98%
Potent and selective TRPV4 antagonist; orally active
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Reversible, competitive and potent TRPV1 antagonist

Chemical Name: 4-[3-(Trifluoromethyl)-2-pyridinyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazinecarboxamide
Purity: ≥98%
Reversible, competitive and potent TRPV1 antagonist
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Selective TRPV4 antagonist

Chemical Name: 2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide
Selective TRPV4 antagonist
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Selective TRPV3 antagonist; brain penetrant

Chemical Name: S)-α-[cis-3-Hydroxy-3-methyl-1-[4-(trifluoromethyl)-2-pyridinyl]cyclobutyl]-2-pyridinemethanol
Purity: ≥98%
Selective TRPV3 antagonist; brain penetrant
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Selective TRPV2 antagonist

Chemical Name: N-(2-Furanylmethyl)-3-[[4-(methylpropylamino)-6-(trifluoromethyl)-2-pyrimidinyl]thio]propanamide
Purity: ≥98%
Selective TRPV2 antagonist
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TRPV1 antagonist

Chemical Name: 4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide
Purity: ≥98%
TRPV1 antagonist
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Potent and selective TRPV1 antagonist

Chemical Name: 3,6-Dihydro-3'-(trifluoromethyl)-N-[4-[(trifluoromethyl)sulfonyl]phenyl]-[1(2H),2'-bipyridine]-4-carboxamide
Purity: ≥98%
Potent and selective TRPV1 antagonist
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Potent and selective TRPV1 antagonist

Chemical Name: 3-Amino-5-[[2-[(2-methoxyethyl)amino]-6-[4-(trifluoromethyl)phenyl]-4-pyrimidinyl]oxy]-2(1H)-quinoxalinone
Purity: ≥97%
Potent and selective TRPV1 antagonist
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Potent TRPV1 antagonist

Chemical Name: N-5-Isoquinolinyl-N'-[[(4-(trifluoromethyl)phenyl]methyl]urea
Purity: ≥98%
Potent TRPV1 antagonist
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Potent TRPV1 antagonist

Chemical Name: N-[4-[[6-[4-(Trifluoromethyl)phenyl]-4-pyrimidinyl]oxy]-2-benzothiazolyl]acetamide
Purity: ≥98%
Potent TRPV1 antagonist
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Potent and selective TRPV4 antagonist

Chemical Name: N-[4-[[4-(1-Methylethyl)-1-piperazinyl]sulfonyl]phenyl]-2-nitro-4-(trifluoromethyl)benzamide hydrochloride
Purity: ≥98%
Potent and selective TRPV4 antagonist
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Non-selective CaV2.1 and 2.2 blocker; also blocks TRPV channels

Chemical Name: Ammoniated ruthenium oxychloride
Non-selective CaV2.1 and 2.2 blocker; also blocks TRPV channels
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Antiallergic; inhibits inflammatory mediator release from mast cells

Chemical Name: 2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenyl]amino]benzoic acid
Purity: ≥98%
Antiallergic; inhibits inflammatory mediator release from mast cells
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