Catalog Number: 5778
Chemical Name: 2-(Dihydrogen phosphate)-L-ascorbic acid sodium salt
Biological Activity
Stable ascorbic acid derivative used in cell culture; in combination with FGF-2, maintains differentiation potential in bone marrow-derived mesenchymal stem cells (MSC) through increased expression of HGF. Also exhibits synergistic protection of hMSCs under oxidative stress in combination with N-acetylcysteine (Cat. No. 5619).
Technical Data
  • M.Wt:
    322.05
  • Formula:
    C6H6Na3O9P
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
    >95%
  • Storage:
    Desiccate at RT
  • CAS No:
    66170-10-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. An in vitro cord formation assay identifies unique vascular phenotypes associated with angiogenic growth factors.
    Falcon et al.
    PLoS One, 2014;9:e106901
  2. Synergistic protection of N-acetylcysteine and ascorbic acid 2-phosphate on human mesenchymal stem cells against mitoptosis, necroptosis and apoptosis.
    Li et al.
    Sci.Rep., 2015;5:9819
  3. L-ascorbic acid 2-phosphate and fibroblast growth factor-2 treatment maintains differentiation potential in bone marrow-derived mesenchymal stem cells through expression of hepatocyte growth factor.
    Bae et al.
    Growth Factors, 2015;33:71

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