Catalog Number: 5619
Chemical Name: (2R)-2-(Acetylamino)-3-mercaptopropanamide
Biological Activity
Glutathione (GSH) precursor and cell permeable antioxidant. Improves neuronal mitochondrial bioenergetics, reduces tissue damage and enhances functional recovery following spinal cord injury in rats. Also enhances behavioral recovery in rats following traumatic brain injury. Neuroprotective.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. N-acetylcysteine amide preserves mitochondrial bioenergetics and improves functional recovery following spinal trauma.
    Patel et al.
    Exp.Neurol., 2014;257:95
  2. N-acetylcysteine amide confers neuroprotection, improves bioenergetics and behavioral outcome following TBI.
    Pandya et al.
    Exp.Neurol., 2014;257:106

The citations listed below are publications that use Tocris products. Selected citations for N-Acetylcysteine amide include:

Showing Results 1 - 1 of 1

  1. The anticancer agent di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes prosurvival autophagy by two mechanisms: persistent induction of autophagosome synthesis and impairment of lysosomal integrity.
    Authors: Gutierrez Et al.
    J Biol Chem
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