2-ThioUTP tetrasodium salt

Name: 2-ThioUTP tetrasodium salt
Brand: Tocris Bioscience
SKU: 3280

Tocris Bioscience | Catalog # 3280

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Citations (6)

Product Documents

Potent and selective P2Y2 agonist

Discontinued Product

3280 has been discontinued. View all P2Y Receptor Agonists products.

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices
Research Areas

Key Product Details

Description

Potent and selective P2Y2 agonist

View all P2Y Receptor Agonists »

Product Description

2-ThioUTP tetrasodium salt is a potent and selective P2Y₂ agonist (EC₅₀ values are 0.035, 0.35 and 1.5 μM for hP2Y₂, hP2Y₄ and hP2Y₆ receptors respectively).

Product Specifications for 2-ThioUTP tetrasodium salt

Molecular Weight

588.13

Formula

C₉H₁₁N₂Na₄O₁₄P₃S

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

2-Thiouridine 5'-triphosphate tetrasodium salt

CAS Number

1343364-70-4

PubChem ID

54591573

InChI Key

QCBCNKBBEOQRRB-ODQFIEKDSA-J

SMILES

[Na+].[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)N1C=CC(=O)NC1=S

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble in water (supplied pre-dissolved at a concentration of 10mM)

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.

Ko Synthesis and potency of novel uracil nucleotides and derivatives as P2Y₂ and P2Y₆ receptor agonists. Bioorg.Med.Chem. 2008 PMID: 18514530
El-Tayeb Synthesis and structure-activity relationships of uracil nucleotide derivatives and analogues as agonists at human P2Y₂, P2Y₄ and P2Y₆ receptors. J.Med.Chem. 2006 PMID: 17125260

Product Documents for 2-ThioUTP tetrasodium salt

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for 2-ThioUTP tetrasodium salt

For research use only

Related Research Areas

Bioactive Lipids and Receptors

Citations for 2-ThioUTP tetrasodium salt

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