27-Hydroxycholesterol

Catalog # Availability Size / Price Qty
3907/10
Cat.No. 3907 - 27-Hydroxycholesterol | C27H46O2 | CAS No. 20380-11-4
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Description: LXR agonist; also ER partial agonist
Alternative Names: 27 OHC, 27 HC

Chemical Name: (3β,25R)-Cholest-5-ene-3,26-diol

Purity: ≥98%

Product Details
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Biological Activity

Liver X receptor (LXR) agonist. Also estrogen receptor partial agonist. Suppresses β-estradiol-mediated breast cancer cell proliferation in vitro. Also increases α-synuclein levels and induces apoptosis in human neuroblastoma cells in vitro. Endogenous cholesterol metabolite.

Technical Data

M.Wt:
402.65
Formula:
C27H46O2
Solubility:
Soluble to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
20380-11-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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