Chemical Name: (17β)-Estra-1,3,5(10)-triene-3,17-diol
Biological Activityβ-Estradiol is an endogenous estrogen receptor (ER) agonist (Ki values are 0.12 and 0.13 nM for ERα and ERβ respectively). Also high affinity ligand at membrane estrogen GPR30 receptors.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells.
Thomas et al.
Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β.
Kuiper et al.
Citations for β-Estradiol
The citations listed below are publications that use Tocris products. Selected citations for β-Estradiol include:
5 Citations: Showing 1 - 5
A mechanical acupuncture instrument mitigates the endoplasmic reticulum stress and oxidative stress of ovariectomized rats.
Authors: Seo Et al.
Integr Med Res 2019;8:187
Selective oestrogen receptor antagonists inhibit oesophageal cancer cell proliferation in vitro.
Identification of Differential ER-Alpha Versus ER-Beta Mediated Activation of eNOS in Ovine Uterine Artery Endothelial Cells.
Authors: Pastore Et al.
Biol Reprod 2016;94:139
Nicotinamide Adenine Dinucleotide Phosphate Oxidase-Mediated Redox Signaling and Vascular Remodeling by 16α-Hydroxyestrone in Human Pulmonary Artery Cells: Implications in Pulmonary Arterial Hypertension.
Authors: Hood Et al.
p130Cas over-expression impairs mammary branching morphogenesis in response to estrogen and EGF.
Authors: Leal Et al.
PLoS One 2012;7:e49817
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