Catalog Number: 2824
Alternate Names: 17 β-Estradiol
Chemical Name: (17β)-Estra-1,3,5(10)-triene-3,17-diol
Biological Activity
Endogenous estrogen receptor (ER) agonist (Ki values are 0.12 and 0.13 nM for ERα and ERβ respectively). Also high affinity ligand at membrane estrogen GPR30 receptors. α-Estradiol (Cat. No. 2823) also available.
Technical Data
  • M.Wt:
    272.38
  • Formula:
    C18H24O2
  • Solubility:
    Soluble to 100 mM in DMSO and to 75 mM in ethanol
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    50-28-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells.
    Thomas et al.
    Endocrinology, 2005;146:624
  2. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β.
    Kuiper et al.
    Endocrinology, 1997;138:863
Citations:

The citations listed below are publications that use Tocris products. Selected citations for β-Estradiol include:

1 Citations: Showing 1 - 1

  1. p130Cas over-expression impairs mammary branching morphogenesis in response to estrogen and EGF.
    Authors: Leal Et al.
    PLoS One 2012;7:e49817
Tocris Small Molecules
Description Application Cat# Citations Images  

β-Estradiol - d3

5528  
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