Catalog Number: 4599
Chemical Name: 3,5-Dihydroxybenzoic acid
Biological Activity
Selective agonist of hydroxycarboxylic acid receptor 1 (HCA1, also known as GPR81) (EC50 ~150 μM). Inhibits lipolysis in wild-type mouse adipocytes. Displays minimal activity at HCA2 (at concentrations >10 mM) and no activity at HCA3, free fatty acid receptor (FFAR) 2 or FFAR3.
Technical Data
  • M.Wt:
    154.12
  • Formula:
    C7H6O4
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    99-10-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. 3,5-dihydroxybenzoic acid, a specific agonist for hydroxycarboxylic acid 1, inhibits lipolysis in adipocytes.
    Liu et al.
    J.Pharmacol.Exp.Ther., 2012;341:794

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