Catalog Number: 1140
Chemical Name: 8-Bromoadenosine-3',5'-cyclic monophosphate sodium salt
Biological Activity
Cell-permeable cAMP analog; activator of protein kinase A. Also available as part of the PKA Tocriset™.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Protein kinase A induces recruitment of active Na+,K+-ATPase units to the plasma membrane of rat proximal convoluted tubule cells.
    Carranza et al.
    J.Physiol., 1998;511:235
  2. Functional modulation of P2X2 receptors by cyclic AMP-dependent protein kinase.
    Chow et al.
    J.Neurochem., 1998;70:2606
  3. Lack of correlation between activation of cyclic AMP-dependent protein kinase and inhibition of contraction of rat vas deferens by cyclic AMP analogs.
    Hei et al.
    Mol.Pharmacol., 1991;39:233
  4. A cyclic AMP analog, 8-Br-cAMP, enhances the induction of pluripotency in human fibroblast cells.
    Wang et al.
    Stem Cell Rev., 2011;7:331
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