8-pCPT-2-O-Me-cAMP-AM

Catalog # Availability Size / Price Qty
4853/100U
Cat.No. 4853 - 8-pCPT-2-O-Me-cAMP-AM | C20H21ClN5O8PS | CAS No. 1152197-23-3
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Description: Selective Epac activator; cell-permeable analog of 8CPT-2Me-cAMP (Cat. No. 1645)
Alternative Names: 007-AM

Chemical Name: 8-(4-Chlorophenylthio)-2'-O-methyladenosine-3',5'-cyclic monophosphate acetoxymethyl ester

Purity: ≥97%

Product Details
Citations (1)
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Biological Activity

Selective Epac activator; cAMP analog. Induces Rap activation and junction tightening in HUVECs; triggers adhesion of Jurkat-Epac1 cells to fibronectin. Stimulates insulin secretion in rat INS-1 cells. More potent, cell-permeable analog of 8CPT-2Me-cAMP (Cat. No. 1645).

This product is a mixture of axial and equatorial isomers. Both isomers give 8CPT-2Me-cAMP after esterase cleavage.

Technical Data

M.Wt:
557.9
Formula:
C20H21ClN5O8PS
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥97%
Storage:
Store at -80°C
CAS No:
1152197-23-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Additional Information

Licensing Caveats:
Sold with the permission of BioLog Life Science Institute.

Product Datasheets

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Citation for 8-pCPT-2-O-Me-cAMP-AM

The citations listed below are publications that use Tocris products. Selected citations for 8-pCPT-2-O-Me-cAMP-AM include:

1 Citation: Showing 1 - 1

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