ABCB8 Antibody

Novus Biologicals | Catalog # NBP3-50123

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit
View all ABCB8 Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide corresponding to a internal portion of human ABCB8.

Reactivity Notes

BLAST analysis was used to suggest cross-reactivity with ABCB8 from human, mouse, and rat based on a 100% homology with the immunizing sequence. Reactivity against homologues from other sources is not known.

Specificity

The antibody detects ABCB8 in cell lysates.

Clonality

Polyclonal

Host

Rabbit

Applications for ABCB8 Antibody

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody has been tested by ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect band approximately 79.9 kDa in size corresponding to ABCB8 by western blotting in the appropriate cell lysate or extract.

Formulation, Preparation, and Storage

Purification

Delipidation and Defibrination

Formulation

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ABCB8

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.

Alternate Names

ATP-binding cassette, sub-family B (MDR/TAP), member 8, EC 3.6.3, EST328128, M-ABC1mitochondrial ABC protein, mitochondrial, Mitochondrial ATP-binding cassette 1

Gene Symbol

ABCB8

Additional ABCB8 Products

Product Documents for ABCB8 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for ABCB8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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