ABCD4 Antibody

Novus Biologicals | Catalog # NBP1-20872

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all ABCD4 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-RDDIDNPDQRISQD corresponding to internal region according to NP_005041.1.

Epitope

C terminus

Specificity

Reported variants represent identical protein: NP_064719.1 NP_064731.1 NP_064720.1 NP_064730.1

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for ABCD4 Antibody

Western Blot: ABCD4 Antibody [NBP1-20872]

Western Blot: ABCD4 Antibody [NBP1-20872]

Western Blot: ABCD4 Antibody [NBP1-20872] - (0.3ug/ml) staining of Jurkat lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected with chemiluminescence.

Applications for ABCD4 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:8000

Western Blot

0.3 - 1 ug/ml
Application Notes
WB: Approx. 70 kDa band observed in lysates of Jurkat and MOLT4 (calculated MW of 68.6 kDa band according to NP_005041.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ABCD4

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding.

Alternate Names

ATP-binding cassette sub-family D member 4, ATP-binding cassette, sub-family D (ALD), member 4, EST352188, P70R69 kDa peroxisomal ABC-transporter, Peroxisomal membrane protein 1-like, Peroxisomal membrane protein 69, PMP69P79R, PMP70-related protein, PXMP1-L, PXMP1LABC41

Entrez Gene IDs

5826 (Human); 19300 (Mouse); 299196 (Rat)

Gene Symbol

ABCD4

UniProt

NP_005041.1 (Human)

Additional ABCD4 Products

Product Documents for ABCD4 Antibody

Certificate of Analysis

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Product Specific Notices for ABCD4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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