Acetylcholinesterase/ACHE Antibody (4E11) - BSA Free

Novus Biologicals | Catalog # NBP1-05146

Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human, Bovine

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 4E11

Format

BSA Free
View all Acetylcholinesterase/ACHE Primary Antibodies »

Product Specifications

Immunogen

C-terminal 10 residues of brain acetylcholinesterase (human and bovine), absent from the erythrocyte enzyme.

Epitope

C-terminal 10 residues (aa 574-583) of brain acetylcholinesterase (DS-AChE and SS-AChE) (1).

Reactivity Notes

Human and Bovine.

Marker

Early Neuronal Development Marker

Specificity

Specific for brain AChE and does not recognize AChE from erythrocytes. The can thus distinguish between mammalian brain AChE and erythrocyte AChE. Weak cross-reactivity with Torpedo marmorata AChE but none with AChE from electric eel or human BtChE.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for Acetylcholinesterase/ACHE Antibody (4E11) - BSA Free

Immunohistochemistry-Paraffin: Acetylcholinesterase/ACHE Antibody (4E11) - BSA Free [NBP1-05146]

Immunohistochemistry-Paraffin: Acetylcholinesterase/ACHE Antibody (4E11) - BSA Free [NBP1-05146]

Immunohistochemistry-Paraffin: Acetylcholinesterase/ACHE Antibody (4E11) - BSA Free [NBP1-05146] - Human placenta stained with NBP1-05146

Applications for Acetylcholinesterase/ACHE Antibody (4E11) - BSA Free

Application
Recommended Usage

Western Blot

1:75

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10mM Phosphate (pH 7.4) and 0.5M NaCl

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Acetylcholinesterase/ACHE

Acetylcholinesterase (AChE, EC.3.1.1.7.) is an enzyme located in the postsynaptic membrane and in the muscle endplates, where it hydrolyses the neurotransmitter acetylcholin. AChE from brain is a tetramer (G4-AChE) with a molecular mass of 320 kDa, AChE from erythrocytes is a dimer (G2-AChE) with a molecular mass of 170 kDa. Detection of higher levels of AChE in amniotic fluid can indicate fetal malformations such as neural tube defects.

Alternate Names

ACHE, ARACHE, N-ACHE

Gene Symbol

ACHE

Additional Acetylcholinesterase/ACHE Products

Product Documents for Acetylcholinesterase/ACHE Antibody (4E11) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Acetylcholinesterase/ACHE Antibody (4E11) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customer Reviews for Acetylcholinesterase/ACHE Antibody (4E11) - BSA Free

There are currently no reviews for this product. Be the first to review Acetylcholinesterase/ACHE Antibody (4E11) - BSA Free and earn rewards!

Have you used Acetylcholinesterase/ACHE Antibody (4E11) - BSA Free?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies