ACTL7B Antibody

Name: ACTL7B Antibody
Brand: Novus Biologicals
SKU: NB100-93366
Price: 399 USD
Availability: InStock

Novus Biologicals | Catalog # NB100-93366

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Product Documents

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

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Product Specifications

Immunogen

Peptide with sequence C-QLKMKPRKVHKIK corresponding to internal region according to NP_006677.1.

Epitope

C-QLKMKPRKVHKIK

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for ACTL7B Antibody

Western Blot: ACTL7B Antibody [NB100-93366]

Western Blot: ACTL7B Antibody [NB100-93366] - (0.03ug/ml) staining of human testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for ACTL7B Antibody

Application

Recommended Usage

Peptide ELISA

Detection limit 1:128000

Western Blot

0.03 - 0.1 ug/ml

Application Notes

WB: Approx. 48 kDa band observed in human testis lysates (calculated MW of 45.2 kDa band according to NP_006677.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ACTL7B

The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known. [provided by RefSeq]

Alternate Names

actin-like 7B, actin-like 7-beta, actin-like protein 7B, Actin-like-7-beta, Tact1

Entrez Gene IDs

10880 (Human)

Gene Symbol

ACTL7B

UniProt

NP_006677.1 (Human)

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Product Documents for ACTL7B Antibody

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Product Specific Notices for ACTL7B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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