AGPAT6 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-85061

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%), Rat (98%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all AGPAT6 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: FAWATLRMERGAKEKNHQLYKPYTNGIIAKDPTSLEEEIKEIRRSGSSKALDNTPEFELSDIFYFCRKGMETIMDDEVTKRFSAEELESW

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for AGPAT6 Antibody - BSA Free

Immunohistochemistry-Paraffin: AGPAT6 Antibody [NBP1-85061]

Immunohistochemistry-Paraffin: AGPAT6 Antibody [NBP1-85061]

Immunohistochemistry-Paraffin: AGPAT6 Antibody [NBP1-85061] - Staining of human adrenal gland shows cytoplasmic positivity in glandular cells.

Applications for AGPAT6 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: AGPAT6

Glycerol-3-phosphate acyltransferase 4 (GPAT4), also known as AGPAT6, is a novel glycerolipid acyltransferase of the ER, which is crucial for the production of milk fat by the mammary gland.

Agpat6 deficiency leads to a reduction in body weight and resistance to both diet-induced and genetically induced obesity. This reduced body weight is associated with increased energy expenditure, reduced triglyceride accumulation in BAT and WAT, reduced white adipocyte size, and lack of adipose tissue in the subdermal region. AGPAT6 fills a unique role in determining triglyceride content and composition in adipose tissue and liver that cannot be compensated by other members of the Agpat family.

Alternate Names

1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acidacyltransferase, zeta), Acyl-CoA:glycerol-3-phosphate acyltransferase 4, DKFZp586M1819,1-acyl-sn-glycerol-3-phosphate acyltransferase zeta, EC 2.3.1.15, glycerol-3-phosphate acyltransferase 4,1-AGP acyltransferase 6, glycerol-3-phosphate acyltransferase 6,1-AGPAT 6, GPAT4,1-acylglycerol-3-phosphate O-acyltransferase 6, LPAAT-zetaLPAATZ, Lysophosphatidic acid acyltransferase zeta, testis spermatogenesis apoptosis-related protein 7, TSARG7

Gene Symbol

AGPAT6

Additional AGPAT6 Products

Product Documents for AGPAT6 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for AGPAT6 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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