alpha 1-Microglobulin Antibody - BSA Free

Novus Biologicals | Catalog # NB100-62165

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunodiffusion

Label

Unconjugated

Antibody Source

Polyclonal Sheep IgG

Format

BSA Free
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Product Specifications

Immunogen

Highly pure human alpha-1-microglobulin, prepared from the urine of patients with chronic renal proteinuria, molecular weight 25-30 kDa

Reactivity Notes

Does not react with:Rat

Localization

Secreted

Specificity

This antibody recognises human alpha-1-microglobulin. No cross-reactivity is observed with urine albumin, retinol binding protein or beta-2-microglobulin.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Scientific Data Images for alpha 1-Microglobulin Antibody - BSA Free

ELISA: alpha 1-Microglobulin Antibody [NB100-62165]

ELISA: alpha 1-Microglobulin Antibody [NB100-62165]

ELISA: alpha 1-Microglobulin Antibody [NB100-62165] - Analysis of HRP conjugate of NB100-62165. Native Human Alpha-1 Microglobulin detected with Sheep anti Human Alpha-1 Microglobulin:HRP

Applications for alpha 1-Microglobulin Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

5.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: alpha 1-Microglobulin

Alpha 1-microglobulin (A1M) is an immunomodulatory protein with a broad spectrum of possible clinical applications and seems a promising marker for evaluation of tubular function. Alpha(1)microglobulin/bikunin precursor specifically interacts with the ORF3 protein of hepatitis E virus and has a direct role in enhancing alpha(1)microglobulin export from the hepatocyte. Bikunin has a role in downregulating PI3 kinase and suppressing tumor invasiveness and metastasis in ovaran cancer cells. I-alpha-I plasma protease inhibitors are assembled from one or two heavy chains (H1, H2 or H3) and one light chain, bikunin. Inter-alpha-inhibitor (I-alpha-I) is composed of H1, H2 and bikunin, inter-alpha-like inhibitor (I-alpha-LI) of H2 and bikunin, and pre-alpha-inhibitor (P-alpha-I) of H3 and bikunin. Interacts with FN1

Alternate Names

A1M, alpha 1Microglobulin, AMBP, EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI

Entrez Gene IDs

259 (Human)

Gene Symbol

AMBP

UniProt

Additional alpha 1-Microglobulin Products

Product Documents for alpha 1-Microglobulin Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for alpha 1-Microglobulin Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

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