AMTB hydrochloride

  ( 4 citations )    
Product Datasheet
Catalog Number:3989
Chemical Name:N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamide hydrochloride
Product Details
Citations (4)
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Reviews
Biological Activity
TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in a rat model (pIC50 = 6.23).
Technical Data
  • M.Wt:
    430.99
  • Formula:
    C23H26N2O2S.HCl
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Purity:
    >99
  • Storage:
    Desiccate at RT
  • CAS No:
    926023-82-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for AMTB hydrochloride include:

4 Citations: Showing 1 - 4
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  1. Efficient entry of cell-penetrating peptide nona-arginine into adherent cells involves a transient increase in intracellular calcium.
    Authors: Melikov Et al.
    Autophagy  2015;471:221
  2. Genetic variants affecting human TRPA1 or TRPM8 structure can be classified in vitro as 'well expressed', 'poorly expressed' or 'salvageable'.
    Authors: Morgan Et al.
    Biosci Rep  2015;35
  3. Antinociceptive activity of transient receptor potential channel TRPV1, TRPA1, and TRPM8 antagonists in neurogenic and neuropathic pain models in mice.
    Authors: Sałat and Filipek
    Biochem J  2015;16:167
  4. Differential Contribution of TRPA1, TRPV4 and TRPM8 to Colonic Nociception in Mice.
    Authors: Mueller-Tribbensee Et al.
    PLoS One  2015;10:e0128242

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