Plasminogen is the precursor of plasmin, an active serine protease that dissolves the fibrin of blood clots and acts in many other processes such as embryonic development, tissue remodeling, inflammation and tumor invasion. Synthesized in the kidney, plasminogen is found in plasma and many extracellular fluids. Activated by u- or t-plasminogen activator, the single-chain plasminogen is converted to plasmin that consists of a disulfide bond-linked heavy chain A and light chain B. Heavy chain A contains 5 kringle domains and light chain B corresponds to the serine protease domain. A fragment consisting of the first 4 kringle domains has been named angiostatin, a novel angiogenesis inhibitor.
Angiostatin Antibody (MM0094-6F34) [Alexa Fluor™ Plus 488]
Novus Biologicals | Catalog # NBP2-12042AFP488
Key Product Details
Species Reactivity
Applications
Label
Antibody Source
Product Specifications
Immunogen
Clonality
Host
Isotype
Applications for Angiostatin Antibody (MM0094-6F34) [Alexa Fluor™ Plus 488]
Western Blot
Formulation, Preparation, and Storage
Purification
Formulation
Preservative
Concentration
Shipping
Stability & Storage
Background: Angiostatin
Alternate Names
Gene Symbol
Additional Angiostatin Products
Product Documents for Angiostatin Antibody (MM0094-6F34) [Alexa Fluor™ Plus 488]
Certificate of Analysis
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Product Specific Notices for Angiostatin Antibody (MM0094-6F34) [Alexa Fluor™ Plus 488]
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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Protocols
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- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars