APBB2 Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-30255

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all APBB2 Primary Antibodies »

Product Specifications

Immunogen

Between 708 and 758

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for APBB2 Antibody - BSA Free

APBB2 Antibody

Western Blot:[NBP3-30255]-

Western Blot:[NBP3-30255]-Detection of human APBB2 by western blot and immunoprecipitation. Samples: Whole cell lysate from HEK293T, HeLa and Jurkat cells. Antibodies: Affinity purified rabbit anti-APBB2 antibody used for WB at 0. 4 µg/ml and 1 µg/ml and used for IP at 6 µg/mg lysate. APBB2 was also immunoprecipitated by rabbit anti-APBB2 antibody, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes and 30 seconds.

Applications for APBB2 Antibody - BSA Free

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-citrate/phosphate buffer, pH 7 to 8

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: APBB2

Proteolytic cleavage of the Amyloid protein precursor (APP) gives rise to the beta-Amyloid and Amyloid A4 proteins, which are present in human platelets. Amyloid deposition is associated with type II diabetes, Down's syndrome and a variety of neurological disorders, including Alzheimer's disease. The Amyloid precursor protein (APP) undergoes alternative splicing, resulting in several isoforms. Proteolytic cleavage of APP leads to the formation of the 4 kDa Amyloid ®/A4 protein. This protein is involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer patients. APLP1 (Amyloid precursor-like protein 1) and APLP2 are structurally similar to APP. Human APLP2 is a membrane- bound sperm protein that contains a region highly homologous to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer disease patients.

Alternate Names

amyloid beta (A4) precursor protein-binding, family B, member 2, amyloid beta A4 precursor protein-binding family B member 2, DKFZp434E033, FE65L1FE65LMGC35575, Fe65-like 1, Protein Fe65-like 1

Gene Symbol

APBB2

Additional APBB2 Products

Product Documents for APBB2 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for APBB2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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