Apelin-17 (human, bovine)

Name: Apelin-17 (human, bovine)
Brand: Tocris Bioscience
SKU: 3007

Tocris Bioscience | Catalog # 3007

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Citations (1)

Product Documents

Endogenous apelin agonist

Discontinued Product

3007 has been discontinued. View all Apelin Receptor Agonists products.

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices
Research Areas

Key Product Details

Description

Endogenous apelin agonist

Alternative Names

K17F,Prepro-61-77-Apelin

View all Apelin Receptor Agonists »

Product Description

Apelin-17 (human, bovine) is an endogenous apelin receptor agonist. Potently inhibits forskolin-stimulated cAMP accumulation (pIC₅₀ = 9.94).

Product Specifications for Apelin-17 (human, bovine)

Molecular Weight

2138.56

Formula

C₉₆H₁₅₆N₃₄O₂₀S

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

217082-57-0

PubChem ID

16130452

InChI Key

SVWSKJCJNAIKNH-MJZUAXFLSA-N

SMILES

[H]N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 1.2mg/ml in water

Calculators

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Mass

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Background References

References are publications that support the biological activity of the product.

Tatemoto Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. Biochem.Biophys.Res.Comms.
De Mota Apelin, a potent diuretic neuropeptide counteracting vasopressin actions through inhibition of vasopressin neuron activity and vasopressin release. Proc.Natl.Acad.Sci. USA
Medhurst Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin. J.Neurochem. 2003 PMID: 12603839

Product Documents for Apelin-17 (human, bovine)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Apelin-17 (human, bovine)

For research use only

Related Research Areas

Chemokines and Receptors

Infectious Diseases

Obesity

Citations for Apelin-17 (human, bovine)

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