NADPH oxidase inhibitor. Demonstrates anti-inflammatory properties in a mouse model of carrageenan-induced pleurisy. Bioactivated by intracellular peroxidases; acts as an antioxidant in endothelial cells and vascular smooth muscle cells.
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Characteristics of the inhibition of NADPH oxidase activation in neutrophils by apocynin, a methoxy-substituted catechol.
Stolk et al.
Am.J.Respir.Cell Mol.Biol., 1994;11:95
Effect of apocynin, a NADPH oxidase inhibitor, on acute lung inflammation.
Impellizzeri et al.
Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant.
Heum?ller et al.
The citations listed below are publications that use Tocris products. Selected citations for Apocynin include:
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