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Apocynin

4663 3 Citations 1 Review Datasheet / COA / SDS
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4663/50
Apocynin | CAS No. 498-02-2 | NADPH Oxidase Inhibitors
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Description: NADPH-oxidase inhibitor

Chemical Name: 4'-Hydroxy-3'-methoxyacetophenone

Purity: ≥99%

Product Details
Citations (3)
Reviews (1)
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Apocynin is a NADPH oxidase inhibitor. Demonstrates anti-inflammatory properties in a mouse model of carrageenan-induced pleurisy. Bioactivated by intracellular peroxidases; acts as an antioxidant in endothelial cells and vascular smooth muscle cells.

Technical Data

M.Wt:
166.17
Formula:
C9H10O3
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥99%
Storage:
Store at RT
CAS No:
498-02-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for Apocynin

The citations listed below are publications that use Tocris products. Selected citations for Apocynin include:

3 Citations: Showing 1 - 3

  1. Tumor-associated neutrophils induce apoptosis of non-activated CD8 T-cells in a TNFα and NO-dependent mechanism, promoting a tumor-supportive environment.
    Authors: Michaeli Et al.
    Oncoimmunology  2017;6:e1356965
  2. The role of Nox1 and Nox2 in GPVI-dependent platelet activation and thrombus formation.
    Authors: Walsh Et al.
    Redox Biol  2014;2:178
  3. Reactive oxygen species and lipid peroxidation inhibitors reduce mechanical sensitivity in a chronic neuropathic pain model of spinal cord injury in rats.
    Authors: Hassler Et al.
    Int J Mol Med  2014;131:413

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Apocynin
By Anonymous on 01/10/2018
Application: Species: Rat

Apocynin is a NADPH oxidase inhibitor. It blocks NADPH oxidase in rat brain slice at 1mM.

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