Apolipoprotein A5 Antibody (C11) - BSA Free

Novus Biologicals | Catalog # NBP3-41491

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # C11

Format

BSA Free
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Product Specifications

Immunogen

Immunized with recombinant Human Apolipoprotein A5 (Uniprot#: Q6Q788; Asp167-Lys335 (Uniprot#: Q6Q788)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for Apolipoprotein A5 Antibody (C11) - BSA Free

Apolipoprotein A5 Antibody (C11)

Immunohistochemistry-Paraffin: Apolipoprotein A5 Antibody (C11) [NBP3-41491] -

Immunohistochemistry-Paraffin: Apolipoprotein A5 Antibody (C11) [NBP3-41491] - DAB staining on IHC-P; Samples: Human Lung Tissue; Primary Ab: 30ug/ml NBP3-41491
Apolipoprotein A5 Antibody (C11)

Western Blot: Apolipoprotein A5 Antibody (C11) [NBP3-41491] -

Western Blot: Apolipoprotein A5 Antibody (C11) [NBP3-41491] - Sample: Recombinant protein.

Applications for Apolipoprotein A5 Antibody (C11) - BSA Free

Application
Recommended Usage

Immunohistochemistry

5-30ug/mL

Immunohistochemistry-Paraffin

5-30ug/mL

Western Blot

0.5-5ug/mL

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS, pH7.4, 50% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Apolipoprotein A5

Apolipoprotein A5 (ApoA5) is a minor apolipoprotein, predominantly associated with HDL and and occasionally with VLDL and chylomicrons. ApoA-5 is a useful indicator of plasma triglyceride levels, a major risk factor for coronary artery disease.

Apo A5 is expressed in the plasma and the liver, where it is involved in the early phase of liver regeneration.

APOA5 mutations can lead to increaased susceptibility to familial hypertriglyceridemia (FHTR), a common inherited disorder where VLDL concentrations are elevated in the plasma. This disorder increases the risk of heart disease, obesity, and pancreatitis. APOA5 mutations can also cause hyperlipoproteinemia type 5 (HLPP5), characterized by increased amounts of chylomicrons/VLDL and decreased amounts of LDL/HDL in the plasma. This disorder often leads to a wide array of syndromes, including insulin-dependent diabetes mellitus, contraceptive steroids, alcohol abuse, and glycogen storage disease type 1A

ApoA5 antibodies are useful for studying lipoprotein processing and a variety of cardiac diseases.

Alternate Names

APOAV, apo-AV, APOA-V, Apolipoprotein A5, apolipoprotein A-V, FLJ97995, MGC126836, RAP3MGC126838, Regeneration-associated protein 3

Gene Symbol

APOA5

Additional Apolipoprotein A5 Products

Product Documents for Apolipoprotein A5 Antibody (C11) - BSA Free

Certificate of Analysis

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Product Specific Notices for Apolipoprotein A5 Antibody (C11) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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