Selective, competitive P2Y2
receptor antagonist. Inactive against a panel of 37 other receptors at a concentration of 10 μ
M. Inhibits ATP-γ
S-induced mucin secretion in bronchial epithelial cells (IC50
= 1 μ
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Nucleotide-mediated mucin secretion from differentiated human bronchial epithelial cells.
Kemp et al.
Am.J.Respir.Cell Mol.Biol., 2004;31:446
The design of P2Y2 antagonists for the treatment of inflammatory diseases.
Abstract of papers, 224th ACS National Meeting, Boston, MA, 2002;