Human P2Y2/P2RY2 (NP_002555) VersaClone cDNA
Human P2Y2/P2RY2 (NP_002555) VersaClone cDNA Summary
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Background: P2Y1/P2RY1
P2RY1 belongs to the family of G protein-coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. P2RY1 functions as a receptor for extracellular ATP and ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C. ADP binding also may lead to a change in platelet shape and possible platelet aggregation.
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