ARFGEF2 Antibody (S07-7H7)

Novus Biologicals | Catalog # NBP3-19573

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S07-7H7 expressed in HEK293
View all ARFGEF2 Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human ARFGEF2 (Uniprot # Q9Y6D5)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

202 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ARFGEF2 Antibody (S07-7H7)

Western Blot: ARFGEF2 Antibody (S07-7H7) [NBP3-19573]

Western Blot: ARFGEF2 Antibody (S07-7H7) [NBP3-19573]

Western Blot: ARFGEF2 Antibody (S07-7H7) [NBP3-19573] - Western blot detection of ARFGEF2 in Hela, 293T lysates using NBP3-19573. Predicted band size: 202kDa. Observed band size: 202kDa.

Applications for ARFGEF2 Antibody (S07-7H7)

Application
Recommended Usage

Western Blot

1/1000-1/5000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ARFGEF2

BIG2 promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF1/ARF5/ARF6 through replacement of GDP with GTP. [from: http://www.genecards.org/cgi-bin/carddisp.pl®gene=ARFGEF2&search=BIG2] ARFGEF2 plays an important role in vesicular and membrane trafficking from the trans-golgi network. It is also involved in the activation of ARFs (1,5, and 6) by accelerating replacement of bound GDP with GTP. It also acts as the activator of ADP-ribosylation factor GTPases that are essential for regulating vesicular traffic among intracellular organelles. [from: http://www.dsi.univ-paris5.fr/genatlas/fiche.php®symbol=ARFGEF2]

Alternate Names

ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldinA-inhibited), ARFGEP2, BIG2brefeldin A-inhibited guanine nucleotide-exchange protein 2, Brefeldin A-inhibited GEP 2, dJ1164I10.1, FLJ23723, PVNH2

Gene Symbol

ARFGEF2

Additional ARFGEF2 Products

Product Documents for ARFGEF2 Antibody (S07-7H7)

Certificate of Analysis

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Product Specific Notices for ARFGEF2 Antibody (S07-7H7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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