ARMER Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-47950

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all ARMER Primary Antibodies »

Product Specifications

Immunogen

ADP-ribosylation factor-like 6 interacting protein 1. (Uniprot# Q15041)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ARMER Antibody - BSA Free

ARMER Antibody - BSA Free

Western Blot: ARMER Antibody - BSA Free [NBP3-47950] -

Western Blot: ARMER Antibody - BSA Free [NBP3-47950] - Mouse lung tissue were subjected to SDS PAGE followed by western blot with (ARMER antibody) at dilution of 1:300

Applications for ARMER Antibody - BSA Free

Application
Recommended Usage

Western Blot

1:500-1:1000
Application Notes
Theoretical Molecular Weight is 22-24 kDa

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ARMER

Apoptosis is important for normal development and tissue homeostasis. It is mediated by various caspases and ultimately results in the activation of endogenous endonucleases that degrade cellular DNA. Although apoptosis induced by endoplasmic reticulum (ER) stress is thought to be mediated by caspase-12, other caspases such as caspase-9 are also thought to be activated following ER stress. Recently, ARMER, a novel integral ER-membrane protein was shown to protect cells from ER stress-induced apoptosis. Analysis of the caspase proteolytic cascade suggests that ARMER acts by inhibiting caspase-9 activity (3), although the mechanism for this remains unkown. It should be noted that ARMER is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.

Alternate Names

ADP-ribosylation factor-like 6 interacting protein, ADP-ribosylation factor-like 6 interacting protein 1, AIP1, Aip-1, apoptotic regulator in the membrane of the endoplasmic reticulum, ARL-6-interacting protein 1, ARL6IPaip-1, ARMER, KIAA0069ADP-ribosylation factor-like protein 6-interacting protein 1

Gene Symbol

ARL6IP1

Additional ARMER Products

Product Documents for ARMER Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for ARMER Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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