Potent and selective corticotropin-releasing factor receptor 2 (CRF2
) antagonist (IC50
values are 1.3 and > 500 nM for CRF2
respectively). Antagonizes CRF2
-mediated inhibition of gastric emptying.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Potent and long-acting corticotropin releasing factor (CRF) receptor 2 selective peptide competitive antagonists.
Rivier et al.
Peptide ligand binding properties of the corticotropin-releasing factor (CRF) type 2 receptor: pharmacology of endogenously expressed receptors, G-protein-coupled sensitivity and determinants of CRF2 receptor selectivity.
Hoare et al.
The effect of lateral septum corticotropin-releasing factor receptor 2 activation on anxiety is modulated by stress.
Henry et al.
The citations listed below are publications that use Tocris products. Selected citations for Astressin 2B include:
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