Mouse CRHR2 (AAA68026) VersaClone cDNA

R&D Systems | Catalog # RDC0114

R&D Systems
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Key Product Details

Species

Mouse

Accession Number

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Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: CRHR2

Official Gene Symbol: CRHR2 Gen Bank Accession Number: NP_001874 Gene ID: 1395 (Human) Gene Map Locus: 7p15.1 (Human) CRHR2 is a novel member of Secretin-family-GPCR proteins that functions as a functional receptor for CRF. It is expressed as 3 isoforms; alpha, beta and gamma. These isoforms primarily differ in their N-terminal sequence and tissue distribution. Apart from CRF, other ligands of CRHR2 include UcnI, UcnII and UcnIII. CRHR2 is involved in stress responses, cardiovascular function and gastric motility. Studies on CRHR2 deficient mice suggested a central anxiolytic effect of CRHR2. Northern Blot analysis detects CRHR2 expression in brain, hypothalamus, heart, GI, lung, skeletal muscle and vasculature.

Long Name

Corticotropin Releasing Hormone Receptor 2

Alternate Names

CRF-RB, CRF2, HM-CRF

Entrez Gene IDs

1395 (Human); 12922 (Mouse); 64680 (Rat)

Gene Symbol

CRHR2

UniProt

Additional CRHR2 Products

Product Documents for Mouse CRHR2 (AAA68026) VersaClone cDNA

Certificate of Analysis

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Product Specific Notices for Mouse CRHR2 (AAA68026) VersaClone cDNA

For research use only

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