ATIC Antibody (OTI1D2)

Novus Biologicals | Catalog # NBP2-01941

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat, Canine, Monkey

Applications

Western Blot, Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI1D2
View all ATIC Primary Antibodies »

Product Specifications

Immunogen

Full length human recombinant protein of human ATIC(NP_004035) produced in HEK293T cell.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

64.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ATIC Antibody (OTI1D2)

Western Blot: ATIC Antibody (OTI1D2) [NBP2-01941]

Western Blot: ATIC Antibody (OTI1D2) [NBP2-01941]

ATIC-Antibody-OTI1D2-Western-Blot-NBP2-01941-img0004.jpg
Flow Cytometry: ATIC Antibody (OTI1D2) [NBP2-01941]

Flow Cytometry: ATIC Antibody (OTI1D2) [NBP2-01941]

Flow Cytometry: ATIC Antibody (OTI1D2) [NBP2-01941] - HEK293T cells transfected with either overexpression plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-ATIC antibody, and then analyzed by flow cytometry.
Western Blot: ATIC Antibody (OTI1D2) [NBP2-01941]

Western Blot: ATIC Antibody (OTI1D2) [NBP2-01941]

Western Blot: ATIC Antibody (OTI1D2) [NBP2-01941] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATIC (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ATIC.
Western Blot: ATIC Antibody (OTI1D2) [NBP2-01941]

Western Blot: ATIC Antibody (OTI1D2) [NBP2-01941]

Western Blot: ATIC Antibody (OTI1D2) [NBP2-01941] - Analysis of extracts (35ug) from 9 different cell lines by using anti-ATIC monoclonal antibody.

Applications for ATIC Antibody (OTI1D2)

Application
Recommended Usage

Flow Cytometry

1:100

Western Blot

1:500-2000

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

0.71 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ATIC

This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq].

Alternate Names

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMPcyclohydrolase, 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotidetransformylase/inosinicase, AICAR, AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme, AICARFT, AICARFT/IMPCHASE, bifunctional purine biosynthesis protein PURH, IMPCHASE, phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase, PURHFLJ93545

Entrez Gene IDs

471 (Human)

Gene Symbol

ATIC

Additional ATIC Products

Product Documents for ATIC Antibody (OTI1D2)

Certificate of Analysis

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Product Specific Notices for ATIC Antibody (OTI1D2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for ATIC Antibody (OTI1D2)

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