B02

Catalog # Availability Size / Price Qty
6392/25
6392/5
Cat.No. 6392 - B02 | C22H17N3O | CAS No. 1290541-46-6
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Description: RAD51 recombinase inhibitor

Chemical Name: 3-(Phenylmethyl)-2-[(1E)-2-(3-pyridinyl)ethenyl]-4(3H)-quinazolinone

Purity: ≥98%

Product Details
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Biological Activity

RAD51 recombinase inhibitor, exhibiting selectivity for human RAD51 over the E.coli homologue RecA (IC50 values are 27.4 μM and >250 μM, respectively). Inhibits homologous recombination and increases cellular sensitivity to DNA damage in vitro. Enhances the therapeutic effect of cisplatin (Cat. No. 2251) on tumor cells in vivo.

Technical Data

M.Wt:
339.4
Formula:
C22H17N3O
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1290541-46-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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