BAPTA AM

Tocris Bioscience | Catalog # 2787

Cell-permeable Ca2+ chelator
Tocris Bioscience

Key Product Details

Description

Cell-permeable Ca2+ chelator
View all Buffers, Chelators and Reagents »

Product Description

BAPTA AM is a selective calcium chelator that is the cell-permeable analog of BAPTA (Cat. No. 2786). Blocks hKv1.5, hKV11.1 (hERG) and hKv1.3 channels (Ki values are 1.23, 1.30 and 1.45 μM respectively). Displays antithrombotic activity in vitro.

F 127 (Cat. No. 6253) for the solubilization of BAPTA AM is also available.

Product Specifications for BAPTA AM

Molecular Weight

764.68

Formula

C34H40N2O18

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl ester)

CAS Number

126150-97-8

PubChem ID

2293

InChI Key

YJIYWYAMZFVECX-UHFFFAOYSA-N

SMILES

O=C(OCOC(C)=O)CN(CC(OCOC(C)=O)=O)C1=CC=CC=C1OCCOC2=CC=CC=C2N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 22.94 30

Preparing Stock Solutions for BAPTA AM

The following data is based on the product molecular weight 764.68.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.3 mM 4.36 mL 21.80 mL 43.59 mL
1.5 mM 0.87 mL 4.36 mL 8.72 mL
3 mM 0.44 mL 2.18 mL 4.36 mL
15 mM 0.09 mL 0.44 mL 0.87 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 212 publications citing the usage of this product.

Product Documents for BAPTA AM

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for BAPTA AM

For research use only

Customer Reviews for BAPTA AM (1)

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  • BAPTA AM used to induce apoptosis
    Name: Anonymous
    Species: Human
    Verified Customer | Posted 01/24/2019
    BAPTA AM being a chelator has been used on our lab multiple times to induce apoptosis in cell cultures.Works great
    BAPTA AM 2787

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