BMS 753

Key Product Details

Product Description

BMS 753 is a RARα-selective agonist (K_i = 2 nM).

Product Specifications for BMS 753

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for BMS 753

The following data is based on the product molecular weight 351.40.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.85 mL	14.23 mL	28.46 mL
5 mM	0.57 mL	2.85 mL	5.69 mL
10 mM	0.28 mL	1.42 mL	2.85 mL
50 mM	0.06 mL	0.28 mL	0.57 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 19 publications citing the usage of this product.

• Taneja Cell-type and promoter-context dependent retinoic acid receptor (RAR) redundancies for RARβ2 and Hoxa-1 activation in F9 and P19 cells can be artefactually generated by gene knockouts. Proc.Natl.Acad.Sci.USA 1996 PMID: 8650243
• Dilworth Ligand-dependent activation of transcription in vitro by retinoid acid receptor α/retinoid X receptor α heterodimers that mimics transactivation by retinoids in vivo. Proc.Natl.Acad.Sci.USA 1999 PMID: 10051583
• Gehin Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists. Chem.Biol. 1999 PMID: 10421757

Product Documents for BMS 753