BMX Antibody (1C6)

Novus Biologicals | Catalog # NBP1-47489

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 1C6
View all BMX Primary Antibodies »

Product Specifications

Immunogen

Purified recombinant fragment of human BMX expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

78 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for BMX Antibody (1C6)

Western Blot: BMX Antibody (1C6)BSA Free [NBP1-47489]

Western Blot: BMX Antibody (1C6)BSA Free [NBP1-47489]

Western Blot: BMX Antibody (1C6) [NBP1-47489] - Western blot analysis using BMX mAb against BMX-hIgGFc transfected HEK293 cell lysate.

Applications for BMX Antibody (1C6)

Application
Recommended Usage

ELISA

1:10000

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Ascites

Formulation

Ascites

Preservative

0.03% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BMX

Etk (epithelial and endothelial tyrosine kinase) is a member of the TEC family of non-receptor protein tyrosine kinase which includes Btk, Itk and TEC. Etk is composed of a pleckstrin domain, an SH3 and SH2 domain and a catalytic kinase domain (1). Etk is implicated in cell adhesion, migration, proliferation, survival as well as signal transduction (2). In PCA, Etk activation by IL-6 is mediated by PI3-K (3). It as also been shown in TNF-induced angiogenesis, TNF activates Etk through TNFR2 (4). Additionally, in the AR pathway, ETtk, FAK and Src form a complex. FAK activates Src which in turn activates Etk by phosphorylating Etk tyrosine residue 566 (5).

Long Name

BMX Non-receptor Tyrosine Kinase

Alternate Names

ETK, NTK38, PSCTK3

Gene Symbol

BMX

Additional BMX Products

Product Documents for BMX Antibody (1C6)

Certificate of Analysis

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Product Specific Notices for BMX Antibody (1C6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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