Boc-QAR-AMC Fluorogenic Peptide Substrate

Substrate for Matriptase, Spinesin, and Prostasin
Catalog # Availability Size / Price Qty
ES014
R&D Systems Fluorogenic Peptide Substrates
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Citations (12)
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Boc-QAR-AMC Fluorogenic Peptide Substrate Summary

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ES014

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

ES014

Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Samples are stable for up to twelve months from date of receipt at -20° C to -70° C. The substrate can be aliquoted and stored -20° C to -70° C in a manual defrost freezer for three months. Avoid repeated freeze-thaw cycles. Protect from exposure to direct light.
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Reconstitution Calculator

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Citations for Boc-QAR-AMC Fluorogenic Peptide Substrate

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

12 Citations: Showing 1 - 10
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  1. Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel's gamma-subunit
    Authors: F Sure, M Bertog, S Afonso, A Diakov, R Rinke, MG Madej, S Wittmann, T Gramberg, C Korbmacher, AV Ilyaskin
    The Journal of Biological Chemistry, 2022;0(0):102004.
    Species: African Clawed Frog
    Sample Types: Whole Cells
    Applications: Bioassay
  2. A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic
    Authors: T Shapira, IA Monreal, SP Dion, DW Buchholz, B Imbiakha, AD Olmstead, M Jager, A Désilets, G Gao, M Martins, T Vandal, CAH Thompson, A Chin, WD Rees, T Steiner, IR Nabi, E Marsault, J Sahler, DG Diel, GR Van de Wal, A August, GR Whittaker, PL Boudreault, R Leduc, HC Aguilar, F Jean
    Nature, 2022;0(0):.
    Species: Chlorocebus aethiops (African Green Monkey)
    Sample Types: Transfected Whole Cells
    Applications: Bioassay
  3. Functionally impaired isoforms regulate TMPRSS6 proteolytic activity
    Authors: SP Dion, A Désilets, G Lemieux, R Leduc
    PLoS ONE, 2022;17(8):e0273825.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Bioassay
  4. Transmembrane serine protease TMPRSS2 implicated in SARS-CoV-2 infection is autoactivated intracellularly and requires N-glycosylation for regulation
    Authors: Y Zhang, S Sun, C Du, K Hu, C Zhang, M Liu, Q Wu, N Dong
    The Journal of Biological Chemistry, 2022;0(0):102643.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Selective targeting of metastatic ovarian cancer using an engineered anthrax prodrug activated by membrane-anchored serine proteases
    Authors: N Duru, NR Pawar, EW Martin, MS Buzza, GD Conway, RG Lapidus, S Liu, J Reader, GG Rao, DM Roque, SH Leppla, TM Antalis
    Oncogene, 2022;119(28):e2201423119.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  6. A Novel Serine Protease Inhibitor PE-BBI Ameliorates Cockroach Extract-Mediated Airway Epithelial Barrier Dysfunction
    Authors: JA Reihill, X Ouyang, Z Yang, LEJ Douglas, M Zhou, T Chen, SL Martin
    Biomolecules, 2020;10(4):.
    Species: N/A
    Sample Types:
    Applications: Bioassay
  7. Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2-Priming Protease TMPRSS2
    Authors: NP Azouz, AM Klingler, V Callahan, IV Akhrymuk, K Elez, L Raich, BM Henry, JL Benoit, SW Benoit, F Noé, K Kehn-Hall, ME Rothenberg
    bioRxiv, 2020;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  8. Structure-activity relationship studies of dipeptide-based hepsin inhibitors with Arg bioisosteres
    Authors: H Kwon, H Ha, H Jeon, J Jang, SH Son, K Lee, SK Park, Y Byun
    Bioorganic chemistry, 2020;0(0):104521.
    Species: N/A
    Sample Types: Fluorogenic Peptide Substrate
    Applications: Bioassay
  9. Design and synthesis of dye-conjugated hepsin inhibitors
    Authors: K Kim, H Kwon, D Choi, T Lim, I Minn, SH Son, Y Byun
    Bioorg. Chem., 2019;89(0):102990.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Bioassay
  10. Transcriptome analysis reveals TMPRSS6 isoforms with distinct functionalities
    Authors: SP Dion, F Béliveau, A Désilets, MG Ghinet, R Leduc
    J. Cell. Mol. Med., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  11. Functional diversity of TMPRSS6 isoforms and variants expressed in hepatocellular carcinoma cell lines
    Authors: SP Dion, F Béliveau, LP Morency, A Désilets, R Najmanovic, R Leduc
    Sci Rep, 2018;8(1):12562.
    Species: Human
    Sample Types: Cell Lysates
  12. A Selective Irreversible Inhibitor of Furin Does Not Prevent Pseudomonas Aeruginosa Exotoxin A-Induced Airway Epithelial Cytotoxicity
    PLoS ONE, 2016;11(7):e0159868.
    Species: Human
    Sample Types: Protein
    Applications: Enzyme Assay

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