receptor agonist that exhibits 5 - 10 fold greater potency than ATP (EC50
= 0.7 μ
M in HEK 293 cells; EC50
values are 3.6 and 285 μ
M for rat and mouse receptors respectively). Exhibits partial agonist activity at P2X1
= 8.7) and P2Y1
receptors and can be used as a photoaffinity label for ATPase.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
- This compound is a mixture of isomers
Pharmacological and molecular characterization of P2X receptors in rat pelvic ganglion neurons.
Zhong et al.
Serum constituents can effect 2'- & 3'-O-(4-benzoylbenzoyl)-ATP potency at P2X7 receptors.
Michel et al.
Exploring the adenine nucleotide binding sites on mitochondrial F1-ATPase with a new photoaffinity probe, 3'-O-(4-Benzoyl)benzoyl adenosine 5'-triphosphate.
Williams and Coleman
Amino acid residues in the P2X7 receptor that mediate differential sensitivity fo ATP and BzATP.
Young et al.
The citations listed below are publications that use Tocris products. Selected citations for BzATP triethylammonium salt include:
Showing Results 1 - 5 of 5