BzATP triethylammonium salt

  ( 5 citations ) ( 1 Review )    
Product Datasheet
Catalog Number:3312
Chemical Name:2'(3')-O-(4-Benzoylbenzoyl)adenosine-5'-triphosphate tri(triethylammonium) salt
Product Details
Citations (5)
Supplemental Products
Reviews
Biological Activity
Prototypic P2X7 receptor agonist that exhibits 5 - 10 fold greater potency than ATP (EC50 = 0.7 μM in HEK 293 cells; EC50 values are 3.6 and 285 μM for rat and mouse receptors respectively). Exhibits partial agonist activity at P2X1 (pEC50 = 8.7) and P2Y1 receptors and can be used as a photoaffinity label for ATPase.

This compound is a mixture of isomers.

Technical Data
  • M.Wt:
    1018.97
  • Formula:
    C24H24N5O15P3.C18H45N3
  • Solubility:
    Soluble in water (supplied pre-dissolved at a concentration of 5mM)
  • Purity:
    >95
  • Storage:
    Store at -20°C
  • CAS No:
    112898-15-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
  • This compound is a mixture of isomers
Product Datasheets
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for BzATP triethylammonium salt include:

5 Citations: Showing 1 - 5
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  1. Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP.
    Authors: Karmakar Et al.
    Nat.Commun.  2016;7:10555
  2. Functional expression of purinergic P2 receptors and transient receptor potential channels by the human urothelium.
    Authors: Shabir Et al.
    Sci Rep  2013;305:F396
  3. Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli.
    Authors: Ilatovskaya Et al.
    Am J Physiol Cell Physiol  2013;305:C1050
  4. Positive allosteric modulation by ivermectin of human but not murine P2X7 receptors.
    Authors: Nörenberg Et al.
    Br J Pharmacol  2012;167:48
  5. Hypertonic stress regulates T cell function via pannexin-1 hemichannels and P2X receptors.
    Authors: Woehrle Et al.
    J Leukoc Biol  2010;88:1181

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Average Rating: 4.5 (Based on 2 reviews)

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  Mouse Anonymous 05/17/2018
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  Rat Anonymous 04/25/2018
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Other Experimental Details

Other Experimental Details It is pre-dissolved in water at 5mM.

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