BzATP triethylammonium salt

Tocris Bioscience | Catalog # 3312

Photoaffinity label for ATPase; also P2X7 agonist and P2X1/P2Y1 partial agonist
Tocris Bioscience

Key Product Details

Description

Photoaffinity label for ATPase; also P2X7 agonist and P2X1/P2Y1 partial agonist
View all P2X Receptor Agonists »

Product Description

BzATP triethylammonium salt is a prototypic P2X7 receptor agonist (EC50 values are 3.6, 7 and 285 μM for rat, human and mouse receptors respectively). Exhibits 5 - 10 fold greater potency than ATP. Exhibits partial agonist activity at P2X1 (pEC50 = 8.7) and P2Y1 receptors and can be used as a photoaffinity label for ATPase.

This compound is a mixture of isomers.

Product Specifications for BzATP triethylammonium salt

Molecular Weight

1018.97

Formula

C24H24N5O15P3.C18H45N3

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

2'(3')-O-(4-Benzoylbenzoyl)adenosine-5'-triphosphate tri(triethylammonium) salt

PubChem ID

71308559

InChI Key

HVOVBTNCGADRTH-WBLDMZOZSA-N

SMILES

NC1=C2C(N([C@@H]3O[C@H](COP(OP(OP(O)([O-])=O)([O-])=O)([O-])=O)[C@@H](OC(C4=CC=C(C(C5=CC=CC=C5)=O)C=C4)=O)[C@H]3O)C=N2)=NC=N1.CC[NH+](CC)CC.CC[NH+](CC)CC.CC[NH+](CC)CC.NC6=C7C(N([C@@H]8O[C@H](COP(OP(OP(O)([O-])=O)([O-])=O)([O-])=O)[C@@H](O)[C@H]8OC(C9=CC=C(C(C%10=CC=CC=C%10)=O)C=C9)=O)C=N7)=NC=N6.CC[NH+](CC)CC.CC[NH+](CC)CC.CC[NH+](CC)CC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble in water (supplied pre-dissolved at a concentration of 5mM)

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 17 publications citing the usage of this product.

Product Documents for BzATP triethylammonium salt

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for BzATP triethylammonium salt

For research use only

Citations for BzATP triethylammonium salt

Customer Reviews for BzATP triethylammonium salt (2)

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  • P2X7 agonist
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vitro
    Verified Customer | Posted 05/17/2018
    Works to activate P2X7 somewhat specifically. Still acts on other P2X receptors, as expected.
  • a potent P2X7R agonist
    Name: Anonymous
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: cultured astrocyte
    Verified Customer | Posted 04/25/2018
    It is pre-dissolved in water at 5mM.
    used at 10uM in cultured cells to block P2X7R.

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