C1qTNF proteins constitute a highly conserved family of Acrp30/Adiponectin paralogs that share a modular organization comprising an N-terminal signal peptide, a short variable region, a collagenous domain and a C-terminal globular domain. C1qTNF proteins are predicted to have trimeric structures that assemble into hexameric and higher order molecular forms. Circulating levels of CTRP1 (C1qTNF1) are elevated in obesity, hypertension, and diabetes but can be decreased in the serum of diet-induced obese mice.
C1qTNF1/CTRP1 Antibody [DyLight 350]
Novus Biologicals | Catalog # AF3145D
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
DyLight 350 (Excitation = 353 nm, Emission = 432 nm)
Antibody Source
Polyclonal Goat IgG
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Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human CTRP1/C1qTNF1
Arg26-Pro281
Accession # Q9BXJ1
Arg26-Pro281
Accession # Q9BXJ1
Specificity
Detects human CTRP1/C1qTNF1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) CTRP4 and rhCTRP5 is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for C1qTNF1/CTRP1 Antibody [DyLight 350]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: CTRP1/C1qTNF1
Long Name
C1q And Tumor Necrosis Factor Related Protein 1
Alternate Names
C1qTNF1, ZSIG37
Gene Symbol
C1QTNF1
Additional CTRP1/C1qTNF1 Products
Product Documents for C1qTNF1/CTRP1 Antibody [DyLight 350]
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for C1qTNF1/CTRP1 Antibody [DyLight 350]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
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- Troubleshooting Guide: Western Blot Figures
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- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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