Calcein AM SummaryCalcein AM is a cell-permeant dye that can be used to determine cell viability and/or cytotoxicity in most eukaryotic cells.
What is Calcein AM?
Calcein AM (structure A) is a non-fluorescent, hydrophilic compound that easily permeates intact, live cells. The hydrolysis of Calcein AM by intracellular esterases produces calcein (structure B), a hydrophilic, strongly fluorescent compound that is well-retained in the cell cytoplasm. Cells grown in black-walled plates can be stained and quantified in less than two hours.
For research use only. Not for diagnostic use.
Citations for Calcein AM
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 2
Filter your results:
Vascular-endothelial response to IDH1 mutant fibrosarcoma secretome and metabolite: implications on cancer microenvironment
Authors: MJ Mao, DE Leonardi
Am J Cancer Res, 2019;9(1):122-133. 2019
Tubuloids derived from human adult kidney and urine for personalized disease modeling
Authors: F Schutgens, MB Rookmaaker, T Margaritis, A Rios, C Ammerlaan, J Jansen, L Gijzen, M Vormann, A Vonk, M Viveen, FY Yengej, S Derakhshan, KM de Winter-, B Artegiani, R van Boxtel, E Cuppen, APA Hendrickx, MM van den He, E Heitzer, H Lanz, J Beekman, JL Murk, R Masereeuw, F Holstege, J Drost, MC Verhaar, H Clevers
Nat. Biotechnol., 2019;37(3):303-313. 2019
No product specific FAQs exist for this product, however you mayView all FAQs
Reviews for Calcein AM
Average Rating: 5 (Based on 3 Reviews)
Have you used Calcein AM?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Robust signal. Cells were treated with drug A for 48 hrs. The fluorescence of Calcein was measured using a plate reader.
Samples were drugged and measured on plate reader after 5 days. The count of florescent cells was plotted against concentration to measure effect