Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Biotin

Antibody Source

Polyclonal Goat IgG
View all CARD11/CARMA1 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human CARD11
Lys263-Ser442
Accession # Q9BXL7

Specificity

Detects endogenous human, mouse, and rat CARMA1 in Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for CARD11/CARMA1 Antibody [Biotin]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CARD11/CARMA1

CARD11 belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

Long Name

Caspase Recruitment Domain-containing Protein 11

Alternate Names

BIMP3, CARMA1

Gene Symbol

CARD11

Additional CARD11/CARMA1 Products

Product Documents for CARD11/CARMA1 Antibody [Biotin]

Certificate of Analysis

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Product Specific Notices for CARD11/CARMA1 Antibody [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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