Caspase-6 Antibody (MCH2 14 1-190) - BSA Free

Novus Biologicals | Catalog # NBP2-66612

Novus Biologicals
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG Clone # MCH2 14 1-190

Format

BSA Free
View all Caspase-6 Primary Antibodies »

Product Specifications

Immunogen

Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant human capase-6 protein and mouse myeloma cells.

Specificity

Detects proenzyme form of human Caspase-6 by Western blot.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG

Scientific Data Images for Caspase-6 Antibody (MCH2 14 1-190) - BSA Free

Western Blot: Caspase-6 Antibody (MCH2 14 1-190) [NBP2-66612]

Western Blot: Caspase-6 Antibody (MCH2 14 1-190) [NBP2-66612]

Western Blot: Caspase-6 Antibody (MCH2 14 1-190) [NBP2-66612] - Analysis using caspase-6 antibody on MCF-7 cells negative (-) and positive (+) for caspase-3 after treatment for 48 hours with thapsigargin.

Applications for Caspase-6 Antibody (MCH2 14 1-190) - BSA Free

Application
Recommended Usage

Western Blot

1:100-1:2000
Application Notes
.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Format

BSA Free

Preservative

0.08% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Caspase-6

Caspase-6 (Cysteine-Requiring Aspartate Proteases) is part of a family of intracellular cysteine proteases that cleave their substrates after aspartic acid residues. These proteases play an integral role in inducing apoptosis in cells. Procaspase-6 (Mch2), a member of the ICE/ced-3 subfamily, is an inactive proenzyme that is activated to form caspase-6 by proteolytic cleavage at certain aspartic acid residues. During cleavage, the N-terminal is removed and the proenzyme is converted into a large (p18) and small (p11) subunits.

Alternate Names

CASP6, Caspase6, Mch2

Gene Symbol

CASP6

UniProt

P55212 (Mouse)

Additional Caspase-6 Products

Product Documents for Caspase-6 Antibody (MCH2 14 1-190) - BSA Free

Certificate of Analysis

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Product Specific Notices for Caspase-6 Antibody (MCH2 14 1-190) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Cysteine Proteases and Regulators

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FAQs

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Associated Pathways

Apoptosis Signaling Pathway Apoptosis Signaling Pathway Thumbnail