Human Catalase ELISA Kit (Colorimetric)

Key Product Details

Product Specifications

Precision

Intra-Assay Precision (Precision within an assay) CV% 5.3 (example only; lot dependent)

Inter-Assay Precision (Precision between assays) CV% 10.0(example only; lot dependent)

Recovery for Human Catalase ELISA Kit (Colorimetric)

Scientific Data Images for Human Catalase ELISA Kit (Colorimetric)

Preparation and Storage

Background: Catalase

Human catalase is an heme-containing peroxisomal enzyme that breaks down hydrogen peroxide to water and oxygen; it is implicated in ethanol metabolism, inflammation, apoptosis, aging and cancer. The 1.5A resolution human enzyme structure, both with and without bound NADPH, establishes the conserved features of mammalian catalase fold and assembly, implicates Tyr370 as the tyrosine radical, suggests the structural basis for redox-sensitive binding of cognate mRNA via the catalase NADPH binding site, and identifies an unexpectedly substantial number of water-mediated domain contacts (1). Because catalase has a low affinity for H2O2, it has been suggested that glutathione peroxidase clears most H2O2 within the erthrocyte and that catalase is of little import. It has been hypothesized that erythrocyte catalase might function to protect heterologous somatic cells against challenge by high levels of exogenous H2O2 (e.g., in areas of inflamation) (2).

Additional Catalase Products

• All Products for Catalase
• Catalase Activity Assays
• Catalase ELISA Kits
• Catalase Lysates
• Catalase Primary Antibodies
• Catalase Proteins and Enzymes

Product Documents for Human Catalase ELISA Kit (Colorimetric)