CCL2/JE/MCP-1 Antibody (001) [DyLight 755]

Name: CCL2/JE/MCP-1 Antibody (001) [DyLight 755]
Brand: Novus Biologicals
SKU: NBP2-90550IR
Price: 539 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-90550IR

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Product Documents

Recombinant Monoclonal Antibody

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Mouse

Applications

ELISA, Sandwich ELISA Detection

Label

DyLight 755 (Excitation = 754 nm, Emission = 776 nm)

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 001 expressed in HEK293

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Product Specifications

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CCL2/JE/MCP-1 (Accession#: NP_035463.1; Met1-Asn148).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for CCL2/JE/MCP-1 Antibody (001) [DyLight 755]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Sandwich ELISA Detection

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CCL2/JE/MCP-1

CCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, lymphocytes, and basophils. Additionally, CCL2 promotes Th2 polarization in CD4⁺ T cells, and CCL2-mediated recruitment of monocytes to sites of inflammation contributes to disease severity in atherosclerosis, multiple sclerosis, and allergic asthma. Endogenous proteolytic trimming of CCL2 at the N-terminus, including the N-terminal pyrrolidone carboxylic acid-modified glutamine, downregulates activity but not receptor binding.

Alternate Names

GDCF-2, HC11, HSMCR30, MCAF, MCP-1, SMC-CF

Gene Symbol

CCL2

Additional CCL2/JE/MCP-1 Products

Product Documents for CCL2/JE/MCP-1 Antibody (001) [DyLight 755]

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Certificate of Analysis

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Product Specific Notices for CCL2/JE/MCP-1 Antibody (001) [DyLight 755]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.