CCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, lymphocytes, and basophils. Additionally, CCL2 promotes Th2 polarization in CD4+ T cells, and CCL2-mediated recruitment of monocytes to sites of inflammation contributes to disease severity in atherosclerosis, multiple sclerosis, and allergic asthma. Endogenous proteolytic trimming of CCL2 at the N-terminus, including the N-terminal pyrrolidone carboxylic acid-modified glutamine, downregulates activity but not receptor binding.
CCL2/JE/MCP-1 Antibody Pair [HRP]
Novus Biologicals | Catalog # NBP2-79448
Recombinant Monoclonal Antibody
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Key Product Details
Assay Type
Sandwich ELISA
Assay Range
2.813-180 pg/ml (example only; lot dependent)
Sensitivity
2.813 pg/ml (example only; lot dependent)
Reactivity
Human
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Product Specifications
Description
Solid Phase sandwich ELISA for the quantitative determination of Human CCL2/JE/MCP-1.
Sample Volume Required
100 ul
Conjugate
HRP
Scientific Data Images for CCL2/JE/MCP-1 Antibody Pair [HRP]
Sandwich ELISA: CCL2/JE/MCP-1 Antibody Pair [HRP] [NBP2-79448] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Kit Contents for CCL2/JE/MCP-1 Antibody Pair [HRP]
- Rabbit Monoclonal Capture Antibody: (Catalog # NBP2-89289)
- Rabbit Monoclonal Detection Antibody (HRP-conjugated): (Catalog # NBP2-89290)
- Standard
Preparation and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Storage of components varies. See protocol for specific instructions.
Background: CCL2/JE/MCP-1
Alternate Names
GDCF-2, HC11, HSMCR30, MCAF, MCP-1, SMC-CF
Gene Symbol
CCL2
Additional CCL2/JE/MCP-1 Products
Product Documents for CCL2/JE/MCP-1 Antibody Pair [HRP]
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for CCL2/JE/MCP-1 Antibody Pair [HRP]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.
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Protocols
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