CCL5/RANTES Antibody Pair [HRP]

Novus Biologicals | Catalog # NBP3-11652

Novus Biologicals
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Key Product Details

Assay Type

Sandwich ELISA

Assay Range

0.78-50 pg/ml (example only; lot dependent)

Sensitivity

0.78 pg/mll (example only; lot dependent)

Reactivity

Human
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Product Specifications

Description

This Human CCL5/RANTES Antibody Pair [HRP] is a solid phase sandwich ELISA for quantitative determination of Human CCL5/RANTES

Sample Volume Required

100 ul

Conjugate

HRP

Scientific Data Images for CCL5/RANTES Antibody Pair [HRP]

ELISA: CCL5/RANTES Antibody Pair [HRP] [NBP3-11652] - Sample standard curve

Kit Contents for CCL5/RANTES Antibody Pair [HRP]

  • Mouse Monoclonal Capture Antibody
  • Mouse Monoclonal Detection Antibody (HRP-conjugated)
  • Standard

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: CCL5/RANTES

RANTES (Regulated-on-activation-normal-T-cell-expressed-and-secreted) is a member of the "intercrine/chemokine" family of cytokines, has been previously shown to be chemotactic for monocytes and T cells of memory/helper phenotype. RANTES has been shown to cause the release of histamine from basophils and activates eosinophils. It also binds to CCR1, CCR3, CCR4 and CCR5 (1). This CC-chemokine enhances antigen-specific T helper (Th) type-1 responses against HIV-1 (2). CC chemokines are small inducible proteins that are related to interleukin 8. In lung adenocarcinoma, RANTES is a predictor of survival while that of interleukin (IL)-8 is associated with a poor prognosis. In several models, tumorigenesis is abolished by RANTES, while it is facilitated by IL-8. Site-directed mutagenesis indicated that regulation of RANTES promoter activity required two nuclear factor (NF)-kappaB response elements but not its activator protein (AP)-1 binding sites (3).

Alternate Names

RANTES, SISd, CCL5, RANTES/CCL5

Gene Symbol

CCL5

Additional CCL5/RANTES Products

Product Documents for CCL5/RANTES Antibody Pair [HRP]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CCL5/RANTES Antibody Pair [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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